Our research operates at the interface of chemistry, physics, and biology, where we seek to uncover the fundamental physical and chemical principles governing complex biological and soft matter systems. By developing theoretical models rooted in statistical mechanics and combining them with multiscale simulations, we investigate how the collective behavior of interacting components gives rise to the structure, organization, and dynamics of complex biological and soft matter systems across multiple length and time scales.
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Our current research is organized into three major thrust areas:

Genome Organization and Nucleic Acid Biology: We develop theoretical and computational models to investigate chromatin organization, gene regulation, and the conformational dynamics of canonical and non-canonical nucleic acid structures, with the goal of understanding genome function and its implications for human disease.
 
Protein Biophysics: We investigate the mechanisms of protein self-assembly and aggregation, with a particular emphasis on understanding their roles in neurodegenerative diseases and other protein-misfolding disorders.
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Soft Matter and Complex Biomolecular Systems: We investigate the physical chemistry of polymers, biomolecular assemblies, and other soft matter systems to uncover the fundamental principles governing self-organization and collective behavior.